The domain within your query sequence starts at position 516 and ends at position 582; the E-value for the 2e8m domain shown below is 3e-7.

AGAPRGHRQPSFRAPMLRLSSKPEEVTAWLQAENFSTVTVRTLGSLMGSQLLHMRPGELQ
MLCPQEA

This is a PDB domain - please see the PDBSUM entry of 2e8m for further annotation